Abstract: According to the informations of subsurface geothermal data,the burial history of source rocks and the main characteristics of the tectonic stages,this paper discusses the relationship between the main period of oil generation-migration and structural settings from the Yujiang Stage of Lower Devonian to Lower Carboniferous in the Central Guangxi Depression.It is believed that the main period of oil generation-migration of the Devonian System came to an end at an earlier time.It is advisable to search for gas rather than oil in structures and other types of traps formed during Dongwu and Indo-China movements.For searching of oil,it is necessary to study structures and other types of traps of pre-Dongwu movement.However,the main period of oil generation-migration of the Lower Carboniferous completed at a later time,oil and gas formed in these source rocks could be trapped in structures and other types of traps of the Indo-China or pre-Indo-China movements,which should be regarded as the principal target for exploration.