Abstract: With the continuous expansion of the scale of water injection and the increase of oil wells exploited with water injection, more and more problems appear during injecting progress, and injection failure problems have become increasingly outstanding. A geological conceptual model is preliminarily established, with the static data of oil wells, combining with the acid fracturing pressure curves, water injection indicating curves, production characteristics and dynamic monitoring data (pressure drop testing curves). On this base, the node factors that causing injection effect variation or failure are found, and different tactics are adopted to solve that problem. Through continuous exploration and summary, one series of countermeasures for water injection failure wells has been gradually formed.