Tahe heavy oil submersible electric pump in present pipe column structure leads to poor blend effect and causes many problems such as short downtime, low well electric pump operation frequency, short service life, high injection-production ratio, low oil utilization rate, high production cost and low economic benefit. Four elements controlling the effect of doped dilute mixtures of heavy oil pump are found, including mixing time, mixing temperature, contact surface and mixing strength. The corresponding countermeasures are put forward and applied in field works. The utilizing rate of dilute oil is improved significantly. The average ratio of injection to production declines by 0.22-0.49. Good economic efficiency shows great potential for future application.